A NEURONAL CULTURE SYSTEM TO DETECT PRION SYNAPTOTOXICITY.

A Neuronal Culture System to Detect Prion Synaptotoxicity.

Synaptic pathology is an early feature of prion as well as other neurodegenerative diseases.Although the self-templating process by which prions propagate is well established, the mechanisms by which prions cause synaptotoxicity are poorly understood, due largely to the absence of experimentally tractable cell culture models.Here, we report that ex

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Molecular characterization of Echinococcus granulosus cysts in north Indian patients: identification of G1, G3, G5 and G6 genotypes.

BACKGROUND: Cystic echinococcosis (CE) caused by the Echinococcus granulosus, is a major public health problem worldwide, including India.The different genotypes of E.granulosus responsible for human hydatidosis have been reported from endemic areas throughout the world.However, the genetic characterization of E.granulosus infecting the human popul

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Advances in molecular imaging and targeted therapeutics for lymph node metastasis in cancer: a comprehensive review

Abstract Lymph node metastasis is a critical indicator of cancer progression, profoundly affecting diagnosis, staging, and treatment decisions.This review article delves into the recent advancements in molecular imaging techniques for lymph nodes, which are pivotal for the early detection and staging of cancer.It provides detailed insights Design W

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